Antibacterial activity of Schiff base complex in vitro

Dr.Hassan Ali Al-Saadi*,Muthana Nahidh Al-Ghanimi** ,Zahraa Hassan Ali Al-Saadi**,Asawer Asaad Al-Zabad***
*Clinical Laboratory Science Department/Pharmacy College/University of Kerbala
**Chemistry deparment/College of Education for Science/University of Kerbala
***College of Veterinary/Kerbala University
(Received February 2012 ,Accepted June 2012 )
Key word: Schiff base complex activity.

Schiff base was prepared by adding (5-(4-Methoxy phenyl azo)-2-hydroxybenzaldehyde) to ethanolic solution and o-aminobenzioc acid, Ni (II) Schiff base complex derived from Schiff base and Ni(II) salt were refluxed . The physical properties were studied. Infrared of Schiff base and the complex were measured. The Ni(II) Schiff base complex have been also tested for their antibacterial activities against several human pathogenic bacteria in vitro .The bacterial species tested included: Staphylococcus aureus Streptococcus pyogenes and Gram-negative, Escherichia coli , Enterobacter aerogenes , Vibrio cholerae, Proteus mirabilis , Salmonella typhi , Serratia marcescens, Pseudomonas aeruginosa.