ASSESSMENT IMPORTANCE OF IL4, C3 AND C4 IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS

Hassan Ali Al-Saadi
Department of Clinical Laboratory Sciences, Pharmacy College, Kerbala University, Kerbala, Iraq

ABSTRACT
Systemic lupus erythematosus (SLE) is an autoimmune disease and a chronic systematic disease with unknown etiology influential more than one million individuals each year. The aim of this study is to substantiation the impact of IL4, C3 and C4 in patients with Systemic Lupus Erythematosus. During the period 2/January/2013 to 1/October/2013, fifty patients with Systemic Lupus Erythematosus that diagnosed by clinic specialists at female with ages ranged between (8-65) years, by using ANA indirect Immunofluorescence test, anti-dsDNA ELISA kit , C3,C4 Radial Immunodiffusion Plate , IL4 ELISA kit. There was an elevated levels of the parameters; ANA, anti-dsDNA and IL-4 that measured in SLE patients which reflect the severity of disease comparing with controls group, also there was importance of ANA, anti-dsDNA, C3, C4 and IL4 in the predictions of disease activity.