Effect of Salicylate On Fusidic Acid and Ciprofloxacin MICs in Staphylococcus aureus

Abbas A.Al-Dulaimi & Mohammed F.Al-Marjani & Hassan A.Al-Saady & Faeza B.Mohammed

Dept of Biology – Collge of Science – Al – Mustansiriyah University – Baghdad – Iraq

Abstract : The susceptibility of five isolates of Staphylococcus aureus which isolated from wound infections were determind against ciprofloxacin & Fusidic acid .The findings have shown that ciprofloxacin & Fusidic acid were highly effective on S. aureus isolates when the Minimum Inhibitory Concentration (MIC) was very low . Then the effect of salicylic acid on the MICs for these antibiotic was studied . Salicylate was shown to increase the resistance among S.aureus isolated when the Minimum Inhibitory Concentration (MIC) was very low . Then the affect of salicylic of acid on the MICs for these antibiotics was studied . Salicylate was shown to increases the resistance among S.aureus isolates to Fusidic acid & Ciprofioxacin .