The effects of Heavy metal (Nickel) on Hematological parameters of laboratory male mice

Abeir C.Al-fatlawi 1 , Merza H. Al-Murshedi 2
1-Faculty of Applied Medical Sciences, University of Karbala
2-Faculty of Science, University of Kufa

Abstract

The present study is aimed to investigate the hematological parameters such as hemoglobin(Hb), red blood cells (RBC), white blood cells (WBC), packed cell volume (PCV), mean cell volume (MCV), mean cell hemoglobin (MCH) and mean cell hemoglobin concentration (MCHC) in the blood of laboratory male mice exposed to sub-lethal concentration of nickel chloride (NiCl2, 6H2 O). The present study shows that the level of hemoglobin, red blood cells and packed cell volume were significantly decreased and simultaneously the white blood cells, mean cell volume, mean cell hemoglobin and mean cell hemoglobin concentration were significantly decreased due to nickel exposure. The present study concluded that the nickel compound affects the hematological parameters of mice by received contaminated water.