(The Bacteriological and the Immunological Study of Diabetic Patients, with and without Foot Ulcer in the Province of Province)
Attending in the Great Hall of Imam Al-Sadiq (PBUH), an MSc. thesis debate was held in the specialty of Medical Laboratories there. The thesis, performed by the researcher (Fatimah Hadi Kadhim), titled as (The Bacteriological and the Immunological Study of Diabetic Patients with and without Foot Ulcer in the Province of Province). The committee of debate was headed by Prof. Jawad K. Traad, PhD- Uni. of Babil-College of Medicine, and its members: Asst.Prof. Ahmed A. Rokan, PhD Uni. of Kerbelaa- College of Pharmacy’ and Asst. Prof Hassan A. Hussain, PhD. Uni. of Kerbelaa’- College of MAS. The thesis was supervised by Prof Suhad H. Mohammad, PhD -Uni. of Kerbelaa’- College of MAS.
The study aims at knowing the difference in the levels of interleukin 17(IL-17A) and other inflammatory indicators, such as TNF Alpha, CRP, ESR and the account of White Blood Cells (WBC), Neutrophils, Lymphocytes; side by side with some other Biochemical Parameters, such as: HbA1c; Urea and Creatinine among patients with second type of diabetes (having a foot Ulcer or not). The study has, also, covered the isolating and diagnosing of the bacteria which cause the foot Ulcer and detecting its sensitivity against some Antibiotic Susceptibility Patterns.
The study concludes that IL17A can be used as a marker in diagnosis of DM in addition to other inflammatory and biochemical markers.
The thesis recommends having more studies in future that aim at:
focusing on the mechanisms responsible for the regulation of Th17 function and their product (IL17A).
isolating and diagnosing the Anaerobic Bacteria from the foot Ulcer and detecting the nature of its sensitivity against the antibiotics.
knowing the mechanism of resistance by the bacteria against antibiotics.