Abstract
Oxidative stresses are affected in an inequality among the creation of reactive oxygen species (ROS) and a biological system’s capability to voluntarily purify responsive intermediates or simply healing the causing destruction. Catalase was an antioxidant enzyme that acting a most important role in monitoring hydrogen peroxide focus at human cells. H2O2 is dissolved in H2O and O2 by CAT, Protecting the oxidative stress cells. It has proposed which helpful polymorphism moves the enzyme action within the gene coding catalase enzyme, thereby reducing safety against oxidative stress. Between February and October 2018 a total of thirty-five patients and fifteen control subjects were gathered. The genotyping of catalase were achieved consuming polymerase chain reaction (PCR) in addition to restriction fragment length polymorphism (RFLP). we tend to determine no significant difference within the genotype frequencies of catalase among patients with hypertension and controls using the P=0.06, OR =7.36 (0.77-69.5)).
Keywords: Hypertension, RFLP, catalase , SNPs. Polymorphisms
