EFFECT ANTI-SPERM ANTIBODY TYPE (IGG&IGA) ON
THE MACROSCOPIC AND MICROSCOPIC SPERM
EXAMINATION SPECIMEN FROM INFERTILE PATIENTS
Hassan Ali Al-Saadi1, Hadi Rasool Hasan AL-Masoodi2 and Zainab Hekmat Abed
Kamona3
1Department of Clinical Laboratory Sciences/ College of Applied Medical Sciences/ 2Department
of Clinical Laboratory Sciences /College of Pharmacy/University of Kerbala,3 Education
Directorate Kerbala/ IRAQ
Abstract:
Male infertility one of the most common health problems with psychological and social effects. This study aims to
investigate the effects of the antisperm antibodies(ASA) on the macroscopic and microscopic parameters of seminal
fluid in some infertile males.The percent of ASA type G (IgG), and (IgA) were measured on the surface of sperms,
macroscopic and microscopic examination of seminal fluid have been measured for infertile patient resorting to
Institute of Embryo Research and Infertility Treatment, Al-Nahrain University, and in the laboratories of Al-Hussain
Hospital /Kerbala. Throughout period then March to August 2011. (419)seminal fluid spaceman are collected from
infertile patient and measurement the percentage of (IgG&IgA) antisperm antibody to (38) sperm agglutination
specimen from infertile patient and comper with (12) fertile men as control group. The results were showed a
significant effect (P< 0.05) of IgG and IgA on a liquefaction time, percentage of progressive motility, sperm
agglutination, and round cells on compared with control group. These results showed a significant decrease (P<0.05)
in the percentage of rapped progressive motility (Grade A) in all groups.A significant increase (P<0.05) in sperm
agglutination and round cell in all groups. Positive correlation with sperm agglutination, morphologically abnormal
sperm percent and round cells. A significant increase (P<0.05) in liquefaction time in the second and the third group.
Key words:ASA,MAR test,IgA,IgG,seminal fluid
Corresponding author:
Hassan Ali Al-Saadi,
Clinical Laboratory Sciences,
College of Applied Medical Sciences,
Kerbala University,
Iraq.