{"id":3581,"date":"2018-07-23T15:52:28","date_gmt":"2018-07-23T12:52:28","guid":{"rendered":"http:\/\/ams.uokerbala.edu.iq\/wp\/?p=3581"},"modified":"2018-07-23T16:00:12","modified_gmt":"2018-07-23T13:00:12","slug":"investigation-of-il6-il10-ifn-%ce%b3-and-tnf-%ce%b1-at-iraqi-patients-with-colon-cancer-suffering-type-2-diabetes","status":"publish","type":"post","link":"https:\/\/ams.uokerbala.edu.iq\/wp\/blog\/2018\/07\/23\/investigation-of-il6-il10-ifn-%ce%b3-and-tnf-%ce%b1-at-iraqi-patients-with-colon-cancer-suffering-type-2-diabetes\/","title":{"rendered":"Investigation of IL6, IL10, IFN-\u03b3 and TNF-\u03b1 at Iraqi patients with colon cancer suffering type-2 diabetes"},"content":{"rendered":"[mhc_section admin_label=&#8221;section&#8221;][mhc_row admin_label=&#8221;row&#8221;][mhc_column type=&#8221;4_4&#8243;][mhc_text admin_label=&#8221;\u0646\u0635&#8221; background_layout=&#8221;light&#8221; text_orientation=&#8221;justified&#8221;]\n<p dir=\"ltr\" style=\"text-align: center\"><span style=\"font-size: 18px\">Investigation of IL6, IL10, IFN-\u03b3 and TNF-\u03b1 at Iraqi patients with colon cancer suffering type-2 diabetes<\/span><\/p>\n<p dir=\"ltr\" style=\"text-align: center\">Hassan A Al-Saadi*<br \/>\nDepartment of Clinical Laboratory Sciences\/Pharmacy College\/KerbalaUniversity\/Kerbala\/Iraq.<\/p>\n<p dir=\"ltr\">ABSTRACT<br \/>\nObjective: Diabetes mellitus is one of the risk factor for all cause of cancer such as colorectal cancer most common among females worldwide. Aimed to investigate the serum levels of IL-6, IL-10 andIFN-\u03b3, TNF-\u03b1 in patients with colon cancer suffering diabetes mellitus. Materials and methods: Fifty patients with colon cancer (21 female and 29 male) with ages ranged between (20-70) years were taken from (Al-Hussain Hospital City\/Kerbala, Digestive and Liver Disease \/Education Hospital Medical City Baghdad and Teaching Oncology Hospital \/Baghdad Medical City\/ Baghdad \/Iraq). Compared with 20 healthy persons. Estimation of CEA, Ca19-9 by Vidas, soTNF-\u03b1, IFN-\u03b3, IL-6 and IL-10 were studied using the enzyme-linked immunosorbent assay (ELISA) method.<br \/>\nResults: Thirty patients among fifty patients of colon cancer (60%) of patients showed a high diabetes mellitus, fasting plasma glucose was \u2265 126mg\/dl.Twenty non-diabetic patients of colon cancer were (40%),observed a significant (p&lt;0.05) increase when comparing the levels of IL-6 and TNF-\u03b1 in diabetic age group (40-59) yrs with age group (60-70)yrs. In the present study, the results revealed a significant (p&lt;0.05) decrease in the level of IFN-\u03b3 when compared no diabetic age group (40-59) with diabetic age group (60-70) yrs.<br \/>\nConclusion: Elevated (CEA ,Ca 19-9 , IL-6, IL-10, IFN-\u03b3 and TNF-\u03b1 )levels were observed in patients with colon cancer that suffering type 2 diabetes , those patients have high risk of developing diabetes ,these tumor markers and cytokines have a role in diagnosisinterpretation this puzzle in patients.<\/p>\n<p dir=\"ltr\"><a href=\"http:\/\/ams.uokerbala.edu.iq\/wp\/wp-content\/uploads\/2018\/07\/Investigation-of-IL6-IL10-IFN-_.2014.pdf\"><img decoding=\"async\" class=\" wp-image-3476 alignnone\" src=\"http:\/\/ams.uokerbala.edu.iq\/wp\/wp-content\/uploads\/2018\/07\/if_24_2302303.png\" alt=\"\" width=\"77\" height=\"77\" srcset=\"https:\/\/ams.uokerbala.edu.iq\/wp\/wp-content\/uploads\/2018\/07\/if_24_2302303.png 128w, https:\/\/ams.uokerbala.edu.iq\/wp\/wp-content\/uploads\/2018\/07\/if_24_2302303-80x80.png 80w\" sizes=\"(max-width: 77px) 100vw, 77px\" \/><\/a><\/p>\n[\/mhc_text][\/mhc_column][\/mhc_row][\/mhc_section]\n","protected":false},"excerpt":{"rendered":"<p>[mhc_section admin_label=&#8221;section&#8221;][mhc_row admin_label=&#8221;row&#8221;][mhc_column type=&#8221;4_4&#8243;][mhc_text admin_label=&#8221;\u0646\u0635&#8221; background_layout=&#8221;light&#8221; text_orientation=&#8221;justified&#8221;] Investigation of IL6, IL10, IFN-\u03b3 and TNF-\u03b1 at Iraqi patients with colon cancer suffering type-2 diabetes Hassan A Al-Saadi* Department of Clinical Laboratory Sciences\/Pharmacy College\/KerbalaUniversity\/Kerbala\/Iraq. ABSTRACT Objective: Diabetes mellitus is one of the risk factor for all cause of cancer such as colorectal cancer most common among females [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"rop_custom_images_group":[],"rop_custom_messages_group":[],"rop_publish_now":"initial","rop_publish_now_accounts":{"facebook_113637584099864_719826108093022":""},"rop_publish_now_history":[],"rop_publish_now_status":"pending","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"ocean_post_layout":"","ocean_both_sidebars_style":"","ocean_both_sidebars_content_width":0,"ocean_both_sidebars_sidebars_width":0,"ocean_sidebar":"","ocean_second_sidebar":"","ocean_disable_margins":"enable","ocean_add_body_class":"","ocean_shortcode_before_top_bar":"","ocean_shortcode_after_top_bar":"","ocean_shortcode_before_header":"","ocean_shortcode_after_header":"","ocean_has_shortcode":"","ocean_shortcode_after_title":"","ocean_shortcode_before_footer_widgets":"","ocean_shortcode_after_footer_widgets":"","ocean_shortcode_before_footer_bottom":"","ocean_shortcode_after_footer_bottom":"","ocean_display_top_bar":"default","ocean_display_header":"default","ocean_header_style":"","ocean_center_header_left_menu":"","ocean_custom_header_template":"","ocean_custom_logo":0,"ocean_custom_retina_logo":0,"ocean_custom_logo_max_width":0,"ocean_custom_logo_tablet_max_width":0,"ocean_custom_logo_mobile_max_width":0,"ocean_custom_logo_max_height":0,"ocean_custom_logo_tablet_max_height":0,"ocean_custom_logo_mobile_max_height":0,"ocean_header_custom_menu":"","ocean_menu_typo_font_family":"","ocean_menu_typo_font_subset":"","ocean_menu_typo_font_size":0,"ocean_menu_typo_font_size_tablet":0,"ocean_menu_typo_font_size_mobile":0,"ocean_menu_typo_font_size_unit":"px","ocean_menu_typo_font_weight":"","ocean_menu_typo_font_weight_tablet":"","ocean_menu_typo_font_weight_mobile":"","ocean_menu_typo_transform":"","ocean_menu_typo_transform_tablet":"","ocean_menu_typo_transform_mobile":"","ocean_menu_typo_line_height":0,"ocean_menu_typo_line_height_tablet":0,"ocean_menu_typo_line_height_mobile":0,"ocean_menu_typo_line_height_unit":"","ocean_menu_typo_spacing":0,"ocean_menu_typo_spacing_tablet":0,"ocean_menu_typo_spacing_mobile":0,"ocean_menu_typo_spacing_unit":"","ocean_menu_link_color":"","ocean_menu_link_color_hover":"","ocean_menu_link_color_active":"","ocean_menu_link_background":"","ocean_menu_link_hover_background":"","ocean_menu_link_active_background":"","ocean_menu_social_links_bg":"","ocean_menu_social_hover_links_bg":"","ocean_menu_social_links_color":"","ocean_menu_social_hover_links_color":"","ocean_disable_title":"default","ocean_disable_heading":"default","ocean_post_title":"","ocean_post_subheading":"","ocean_post_title_style":"","ocean_post_title_background_color":"","ocean_post_title_background":0,"ocean_post_title_bg_image_position":"","ocean_post_title_bg_image_attachment":"","ocean_post_title_bg_image_repeat":"","ocean_post_title_bg_image_size":"","ocean_post_title_height":0,"ocean_post_title_bg_overlay":0.5,"ocean_post_title_bg_overlay_color":"","ocean_disable_breadcrumbs":"default","ocean_breadcrumbs_color":"","ocean_breadcrumbs_separator_color":"","ocean_breadcrumbs_links_color":"","ocean_breadcrumbs_links_hover_color":"","ocean_display_footer_widgets":"default","ocean_display_footer_bottom":"default","ocean_custom_footer_template":"","ocean_post_oembed":"","ocean_post_self_hosted_media":"","ocean_post_video_embed":"","ocean_link_format":"","ocean_link_format_target":"self","ocean_quote_format":"","ocean_quote_format_link":"post","ocean_gallery_link_images":"on","ocean_gallery_id":[],"footnotes":""},"categories":[72,71],"tags":[],"class_list":["post-3581","post","type-post","status-publish","format-standard","hentry","category-72","category-71","entry"],"aioseo_notices":[],"jetpack_featured_media_url":"","rttpg_featured_image_url":null,"rttpg_author":{"display_name":false,"author_link":"https:\/\/ams.uokerbala.edu.iq\/wp\/blog\/author\/"},"rttpg_comment":0,"rttpg_category":"<a href=\"https:\/\/ams.uokerbala.edu.iq\/wp\/blog\/category\/%d8%a8%d8%ad%d9%88%d8%ab-%d8%a7%d9%84%d8%aa%d8%ad%d9%84%d9%8a%d9%84%d8%a7%d8%aa\/\" rel=\"category tag\">\u0628\u062d\u0648\u062b \u0627\u0644\u062a\u062d\u0644\u064a\u0644\u0627\u062a<\/a> <a href=\"https:\/\/ams.uokerbala.edu.iq\/wp\/blog\/category\/%d8%a8%d8%ad%d9%88%d8%ab\/\" rel=\"category tag\">\u0628\u062d\u0648\u062b<\/a>","rttpg_excerpt":"[mhc_section admin_label=&#8221;section&#8221;][mhc_row admin_label=&#8221;row&#8221;][mhc_column type=&#8221;4_4&#8243;][mhc_text admin_label=&#8221;\u0646\u0635&#8221; background_layout=&#8221;light&#8221; text_orientation=&#8221;justified&#8221;] Investigation of IL6, IL10, IFN-\u03b3 and TNF-\u03b1 at Iraqi patients with colon cancer suffering type-2 diabetes Hassan A Al-Saadi* Department of Clinical Laboratory Sciences\/Pharmacy College\/KerbalaUniversity\/Kerbala\/Iraq. ABSTRACT Objective: Diabetes mellitus is one of the risk factor for all cause of cancer such as colorectal cancer most common among females&hellip;","_links":{"self":[{"href":"https:\/\/ams.uokerbala.edu.iq\/wp\/wp-json\/wp\/v2\/posts\/3581","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ams.uokerbala.edu.iq\/wp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ams.uokerbala.edu.iq\/wp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ams.uokerbala.edu.iq\/wp\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/ams.uokerbala.edu.iq\/wp\/wp-json\/wp\/v2\/comments?post=3581"}],"version-history":[{"count":3,"href":"https:\/\/ams.uokerbala.edu.iq\/wp\/wp-json\/wp\/v2\/posts\/3581\/revisions"}],"predecessor-version":[{"id":3587,"href":"https:\/\/ams.uokerbala.edu.iq\/wp\/wp-json\/wp\/v2\/posts\/3581\/revisions\/3587"}],"wp:attachment":[{"href":"https:\/\/ams.uokerbala.edu.iq\/wp\/wp-json\/wp\/v2\/media?parent=3581"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ams.uokerbala.edu.iq\/wp\/wp-json\/wp\/v2\/categories?post=3581"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ams.uokerbala.edu.iq\/wp\/wp-json\/wp\/v2\/tags?post=3581"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}