College of Science, Misan discussed a master dissertation on the design of delivery systems to improve the stability of biologically active materials capable of retaining volatile components and improving their biological efficacy by the postgraduate student, Ms. Maryam Kadhim Taher.
The dissertation aimed designing a model of a drug release system using a nanogel based on an emulsion of clove oil, as well as preparing and characterizing the emulsion nanogel using Fourier transform infrared spectroscopy (FTIR), nuclear magnetic resonance (1H-NMR), dynamic light scattering (DLS), field emission scanning electron microscopy (FESEM), with studying the biological activities of the emulsion nanogel by studying the drug release of the emulsion nanogel in SGF, SIF and buffer solution and studying the anti-inflammatory effects of the emulsion nanogel.
The dissertation reviewed that the clove nanogel is biocompatible with red blood cells in the hemolytic activity experiment, with no hemolytic reaction observed, and it also showed antibacterial activity against S.aureus and E.coli. Also, all concentrations of clove nanogel had no effect on cytokine secretion by macrophage cell line, no inflammatory effects and no antigen.
