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Basrah University’s Ph.D. Thesis: On Relation between CRISPR System & Some Antibiotic Resistance Genes

College of Science, University of Basrah discussed a Ph.D. thesis on the molecular investigation of the CRISPR system and some antibiotic resistance genes in Escherichia coli bacteria isolated from patients with urinary tract infection by the postgraduate student, Mr. Ahmed Jassim Muhammad.

The thesis aimed at identifying the ability of bacteria to produce Extended Spectrum Beta Lactamase (ESBLs) and Carbapenemase enzymes and to determine the distribution of the CRISPR system in bacterial isolates.

The thesis demonstrated that the (CRISPR) system is present in 87% of the Archaea genome and in 50% of the bacterial genome and has a major role in the defense mechanism as a natural adaptive immunity in E. coli bacteria.