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Relationship between thymosin β4 & IL-10 in systemic lupus erythematous patients
correlated with (Sledai) in Kerbala Governorate

Hadi Rasool Hasan AL-Masoodi

Department of Clinical Laboratory Sciences, Pharmacy College, Kerbala University, Kerbala, Iraq.
A B S T R A C T
This study included study of thirty SLE female patients that diagnosed by clinic specialists by using (SLEDAI) taken from
(Al- Hussein Medical City/Kerbala/ IRAQ) During the period March/2013 to April /2014. Control group consisted of 10
healthy woman who matched in age with patients, and haven’t history for this disease. The result shows a significant
decreasing in concentration of thymosin-β 4 & circulating complement factors ( C3&C4) in active SEL patients compare in
control while IL-10 is predominantly an anti-inflammatory cytokine were significantly increased in SLE patients and to be
associated with anti ANA &-dsDNA antibodies and disease activity measured using the SLE Disease Activity Index
(SLEDAI)
Keywords: Thymosin-β 4, circulating complement factors (C3&C4), SLE patients, IL-10

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