Hormonal studies of some herbs medicine extract (Salvia Officinalis) and its effect on total body weights and some reproductive organs in the mature female mice

Abstract:
Present investigation was designed to show the influence of quotation of Salvia officinalis on
some reproductive organs for female mice. Three groups of this animals (6each) treated orally
with quotation of the herb in two different doses (30 and 60 mg/kg) respectively for four weeks.
The present study showed significant differences (P≤0.05) in body weight for both groups as
compared to control group, also significant differences (P≤0.05) in ovary and uterus only in the
group treated with high dose as compared to control group. However significant differences
(P≤0.05) found in reproductive hormone (FSH, LH) for both groups treated with Salvia officinalis
as compared to control group. Histological study showed a remarkable increase in number of
ovarian follicles, increase growth and development of oocyte and zona granulosa for groups
treated with Salvia officinalis as compared to control group.