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Diyala University’s Master’s Dissertation: On Role of Physiological Variations & Genetic Polymorphisms of Cytochrome P450 Genes in Diabetic Patients

College of Education for Pure Sciences, University of Diyala discussed a master dissertation on the role of physiological variations and genetic polymorphisms of some cytochrome P450 genes in type 2 diabetes patients in the governorate by the postgraduate student, Mr. Saleh Abdul Qader Abd Al-Toma.

The dissertation aimed at evaluating the role of some physiological indicators and determining the genetic polymorphisms of some cytochrome P450 Genes, namely the CYP17A1 and CYP2C8 Genes, in patients with type 2 diabetes and healthy people.

The dissertation highlighted that the statistical analysis reviewed that there were statistical differences in the levels of (FBS, HBA1C Urea, Creatinine TG) between the two study groups, while the results of the study reviewed the presence of genetic variation at the C/A/T rs6163 variant site in the CYP17A1 Gene in the group of patients with type 2 diabetes and the healthy group.