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Kufa University’s Ph.D. Thesis: On Effect of Estrogen Receptor 2 Genetic Polymorphisms on Coronary Artery Stiffness Index

College of Medicine, University of Kufa discussed a Ph.D. thesis on the effect of estrogen receptor 2 genetic polymorphisms on the atherosclerosis index and coronary artery disease by the postgraduate student, Ms. Rasha Farhoud Madloul included.

The thesis reviewed determining the effect of genetic polymorphisms of estrogen receptor 2 on coronary heart disease and indicators of atherosclerosis, as well as the effect of haplotype analysis and evaluating the contribution of the combined effect of these variables with the clinical and vital signs associated with the disease and studying the close association between them in Iraqi population.

The thesis indicated that there was a noticeable increase in the frequency of the genotype in these patients, and the odds ratios, along with their confidence intervals and probability values, were very prominent.

The thesis demonstrated that people with altered genetic patterns may be several times more at risk of contracting the disease compared to those who have not been exposed to a genetic change.